I was delighted to chair the panel meeting on patient enrolment strategies. The audience agreed that patient centricity is largely a concept and advocacy groups are often only considered by sponsor marketing departments. Protocols are demanding and often without enough attention paid to practical patient issues. They felt that many trials go wrong from site selection. Potentially good sites aren’t considered if not obviously known. They stated the feasibility process is not functional at any level. Many sponsors require it to be done by the CRO for free, so its minimal. CROs know if the sponsors approve the sites on that basis then it’s likely new sites will be needed. Sites get many feasibility questionnaires, and often they are not clear. They complete them accordingly. They stated they often don’t get any response. Large sites may take on several trials and just recruit into whichever one in any disease is the easiest. There is much to be improved.
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